Uninstalled both the base and enhanced modules. Re-installed and loaded. The load time didn't look like a compile took place so not convinced the uninstall actually deleted everything. Anyway - spawn in, power on batteries and GPU, start IRS align, go to ACARS, select simbrief import and then PENDING.
To be clear - the fact that it seems to work for many others suggests there is something in the environment of those of us with the problem that causes the issue.
To that end - a little context for my setup:
Steam install, Spad Next, Track-IR, Navigraph, FSUIPC - aside from that I don't this there is anything too weird.
One other thing - I have seen people say weather radar is functioning but when I turn it on I get what looks like a test pattern and no sweeps.
Thanks