I use Spad and the profile is specific to the Inibuilds A340; that profile isn't used on any other aircraft, each one has its own, and the MSFS2024 controls aren't used.
Yesterday I did a flight of almost 9 hours, with a snippet of spad.next and the latest beta version of Spad.next (the stable version is not yet compatible with Inibuilds CDUs) and it worked perfectly, there was no screen freezing
Same here. For my next flight, I'll use the MCDU through Spad.next, without SimApp Pro, to see if the problem disappears. Latest SimApp Pro update and latest MCDU firmware (1.04)