I found the issue. The key P is associated to PAUSE on my system. Obviously, this is not caught. Unpausing with the associated key will resume the simulation. So, it was not really a crash as I thought, just a pause.
The simulation crashes as soon as I enter LIPZ as departure on the INIT page. This does not happen with EDDM. The version is the current update. And, yes, I deleted the WASM folder.